生物活性CW069 是一種變構選擇性microtubule motor protein HSET抑制劑，IC50為75 μM, 其選擇性顯著高于KSP.
體外研究CW069 increases multipolar spindles in N1E-115 cells with supernumerary centrosomes without altering bipolar spindle morphology in normal human dermal fibroblast cells. CW069 inhibits growth in cancer N1E-115 cells with IC50 of 10 μM, but not in NHDF or primary human bone marrow cells.
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